There is no cure for CKD, but good self-care slows it down. Be aware of signs that your CKD may be getting worse. Call your doctor right away if you notice any of these things happening in your body: You are urinating less or not at all. You see blood in your urine or notice that your urine is red or brown. Your legs or feet are swollen. You vomit or don’t feel hungry. You feel weak and/or get tired easily. You feel confused. You have a seizure or faint.